Publications
2007
Link to A. Hoenger 2007 Publications
Blackler, A.R., M.S. Ladinsky and C.C. Wu (2007). A proteomic method for the enrichment of membrane embedded proteins and identification of transmembrane domains. Submitted
Hoog, J.L., C. Schwartz, A.T. Noon, E.T. O'Toole, D.N. Mastronarde, J.R. McIntosh and C. Antony (2007). Organization of interphase microtubules in fission yeast analyzed by electron tomography. Developmental Cell 12: 349-361.
Ladinsky, M.S. and K.E. Howell (2007). Electron tomography of immunolabeled cryosections. Methods in Cell Biology 79: 543-548.
Mogelsvang, S., M.S. Ladinsky, and K.E. Howell (2007). Fatty acid-induced lipoapoptosis, a role for Golgi sphingomyelin and glycosphingolipids. Submitted
Morphew, M.K. (2007). 3D immunolocalization with plastic sections. Methods in Cell Biology 79: 492-413.
Muller-Reichert, T., M. Srayko, A. Hyman, E.T. O'Toole and K. McDonald (2007). Correlative light and electron microscopy of early Caenorhabditis elegans embryos in mitosis. Methods in Cell Biology 79: 101-119.
O'Toole, E.T., T.H. Giddings Jr. and S.K. Dutcher (2007). Understanding microtubule organizing centers by comparing mutant and wild-type structures with electron tomography. Methods in Cell Biology 79: 125-143.
Sandberg, K. and M. Braga (2007). Segmentation of thin structures in electron micrographs using orientation fields. Journal of Structural Biology 157: 403-415.
2006
Link to A. Hoenger 2006 Publications
Canty, E.G., T. Starborg, Y. Lu, S.M. Humphries, D.F. Holmes, R.S. Meadows, A. Huffman, E.T. O'Toole and K.E. Kadler (2006). Actin filaments are required for fibropositor-mediated collagen fibril alignment in tendon. Journal of Biological Chemistry 15: 38592-38598.
Ladinsky, M.S., J.M. Pierson and J.R. McIntosh (2006). Vitreous cryosectioning of cells, facilitated by a micromanipulator. Journal of Microscopy 224: 129-134.
Nicastro, D., C. Schwartz, J. Pierson, R. Gaudette, M.E. Porter and J.R. McIntosh (2006). The molecular architecture of axonemes revealed by cryoelectron tomography. Science. 313: 944-948.
Nakanishi, H., M. Morishita, C.L. Schwartz, A. Coluccio, J. Engebrecht and A.M. Neiman (2006). Phospholipase D and the SNARE Sso1p are necessary for vesicle fusion during sporulation in yeast. Journal of Cell Science. 119: 1406-1415.
Pelletier, L., E.T. O'Toole, A. Schwager, A.A. Hyman and T. Muller-Reichert (2006). Centriole assembly in Caenorhabditis elegans. Nature. 444: 619-623.
Shimogawa, M.M., B. Graczyk, M.K. Gardner, S.E. Francis, E.A. White, M. Ess, J.N. Volk, C. Ruse, S. Niessen, J.R. Yates, III, E.G. Muller, K. Bloom, D.J. Odde and T.N. Davis (2006). Mps1 phosphorylation of dam1 couples kinetochores to microtubule plus ends at metaphase. Current Biology. 16: 1489-1501.
Srayko, M., E.T. O'Toole, A.A. Hyman and T. Muller-Reichert (2006). Katanin disrupts the microtubule lattice and increases polymer number in C. elegans meiosis. Current Biology. 16: 1944-1949.
Storchova, Z., A. Breneman, J. Cande, J. Dunn, K. Burbank, E.T. O'Toole and D. Pellman (2006). Genome-wide genetic analysis of polyploidy in yeast. Nature. 443: 541-547.
Zheng, L., C. Schwartz, L. Wee and S. Oliferenko (2006). The fission yeast TACC-related protein, Mia1p/Alp7p, is required for formation and maintenance of persistent microtubule-organizing centers at the nuclear envelope. Molecular Biology of the Cell. 17:2212-2222.
2005
Caldwell, J.P., D.N. Mastronarde, J.L. Woods, and W.G. Bryson (2005). The three-dimensional arrangement of intermediate filaments in Romney wool cortical cells. Journal of Structural Biology. 151:298-305.
Mastronarde, D.N. (2005). Automated electron microscope tomography using robust prediction of specimen movements. Journal of Structural Biology. 152:36-51.
McIntosh, J.R., D. Nicastro and D.N. Mastronarde (2005). New views of cells in 3D: an introduction to electron tomography. Trends in Cell Biology. 15:43-51.
Muller, E.G.D., B.E. Snydsman, I. Novik, D.W. Hailey, D.R. Gestaut, C.A. Niemann, E.T. O'Toole, T.H. Giddings, Jr., B.A. Sundin and T.N. Davis (2005). The organization of the core proteins of the yeast spindle pole body. Molecular Biology of the Cell. 16:3341-3352.
Nicastro, D., J.R. McIntosh and W. Baumeister (2005). 3D structure of eukaryotic flagella in a quiescent state revealed by cryo-electron tomography. Proceedings of the National Academy of Sciences. 102: 15889-15894.
Ozlu, N., M. Srayko, K. Kinoshita, B. Habermann, E.T. O'Toole, T. Müller-Reichert, N. Schmalz, A. Desai and A.A. Hyman (2005). An essential function of the C. elegans ortholog of TPX2 is to localize activated aurora A kinase to mitotic spindles. Developmental Cell. 9:237-248.
Snyder, C.M., G. Mardones, M.S. Ladinsky and K.E. Howell (2005). GMx33 associates with the trans-Golgi matrix in a dynamix manner and sorts within tubules exiting the Golgi. Molecular Biology of the Cell. 17:511-524.
Stemm-Wolf, A.J., G. Morgan, T.H. Giddings, Jr., E.A. White, R. Marchione, H.B. McDonald and M. Winey. (2005). Basil body duplication and maintenance require one member of the Tetrahymena thermophila centrin gene family. Molecular Biology of the Cell. 16:3606-3619.
Tucker, M., M. Sieber, M. Morphew and M. Han (2005). The Caenorhabditis elegans aristaless orthologue, alr-1, is required for maintaining the functional and structural integrity of the amphid sensory organs. Molecular Biology of the Cell. 16:4695-4704.
Winey, M., G.P. Morgan, P.D. Straight, T.H. Giddings, Jr. and D.N. Mastronarde (2005). Three-dimensional ultrastructure of Saccharomyces cerevisiae meiotic spindles. Molecular Biology of the Cell. 16:1178-1188.
Yoder, T.J., M.A. McElwain, S.E. Francis, J. Bagley, E.G.D. Muller, B. Pak, E.T. O'Toole, M. Winey and T.N. Davis (2005). Analysis of a spindle pole body mutant reveals a defect in biorientation and illuminates spindle forces. Molecular Biology of the Cell. 16:141-152.
2004
Marsh, B.J., N. Volkmann, J.R. McIntosh and K.E. Howell (2004). Direct continuities between cisternae at different levels of the Golgi complex in glucose-stimulated mouse islet beta cells. Proceedings of the National Academy of Sciences. 101:5565-5570.
Yokohama, R., E.T. O'Toole, S. Ghosh and D.R. Mitchell (2004). Regulation of flagellar dynein activity by a central pair kinesin. Proceedings of the National Academy of Sciences. 101:17398-17403.
Mogelsvang, S., B.J. Marsh, M.S. Ladinsky and K.E. Howell (2004). Predicting function from structure: 3D structure studies of the mammalian Golgi complex. Traffic. 5:338-345.
Zahn, T.R., J.R. Angleson, M.A. MacMorris, E. Domke, J.F. Hutton, C. Schwartz and J.C Hutton (2004). Dense core vesicle dynamics in Caenorhabditis elegans neurons and the role of kinesin UNC-104. Traffic. 5: 544-559.
2003
O'Toole, E.T., K.L. McDonald, J. Mantler, J.R. McIntosh, A.A. Hyman and T. Müller-Reichert (2003). Morphologically distinct microtubule ends in the mitotic centrosome of Caenorhabditis elegans. Journal of Cell Biology. 163:451-456.
Sandberg, K., D.N. Mastronarde, and G. Beylkin (2003). A fast reconstruction algorithm for electron microscope tomography. Journal of Structural Biology. 144:61-72.
Morphew, M.K. and J.R. McIntosh (2003). The use of filter membranes for high pressure freezing of cell monolayers. Journal of Microscopy. 212:21-25.
Müller-Reichert, T., E.T. O'Toole, H. Hohenberg and K. McDonald (2003). Cryoimmobilization and three-dimensional visualization of C. elegans ultrastructure. Journal of Microscopy. 212:71-80.
Müller-Reichert, T., E. Sassoon, E.T. O'Toole, M. Romao, A.J. Ashford, A.A. Hyman and C. Antony (2003). Analysis of the distribution of the kinetochore protein Nde10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles. Chromosoma. 111:417-428.
Nickas, M., C. Schwartz, and A. Neiman (2003). ADY4P and SPO74P are components of the meiotic spindle pole body that promote growth of the prospore membrane in yeast. Eukaryotic Cell. 2(3):431-445.
O'Toole, E.T.. T.H. Giddings, J.R. McIntosh and S.K. Dutcher (2003). Three-dimensional organization of basal bodies from wild type delta tubulin deletion strains of Chlamydomonas reinhardtii. Molecular Biology of the Cell. 14:2999-3012.
Roberts, P., S. Moshitch-Moshkovitz, E. Kvam, E.T. O'Toole, M. Winey and D.S. Goldfarb (2003). Piecemeal microautophagy of nucleus in Saccharomyces cerevisiae. Molecular Biology of the Cell 14(1):129-141.
Paoletti, A., N. Bordes, R. Haddad, C. Schwartz, F. Chang and M. Bornens (2003). Fission yeast cdc31p is a component of the half-bridge and controls SPB duplication. Molecular Biology of the Cell 14(7):2793-2808.
Stanlis, K.K.H. and J.R. McIntosh (2003). Single-strand DNA aptamers as probes for protein localization in cells. Journal of Histochemistry & Cytochemistry. 51:797-808.
2002
Burns, C.G., R. Ohi, S. Mehta, E.T. O'Toole, M. Winey, T.A. Clark, C.W. Sugnet, M. Ares Jr. and K.L. Gould (2002). Removal of a single alpha-tubulin gene intron suppresses cell cycle arrest phenotypes of splicing factor mutations in Saccharomyces cerevisiae. Molecular Biology of the Cell 22(3):801-15.
Clemett, S.J., K.L. Thomas-Keprta, J. Shimmin, M. Morphew, J.R. McIntosh, D.A. Bazylinsky, J. Kirschvink, S.J. Wentworth, D.S. McKay, K. Vali, E.K. Gibson and C.S. Romanek (2002). Crystal morphology of MV-1 magnetite. American Mineralogist 87:1727-1730.
Duman, J.G., N.J. Pathak, M.S. Ladinsky, K.L. McDonald and J.G. Forte (2002). Three-dimensional reconstruction of cytoplasmic membrane networks in parietal cells. Journal of Cell Science 115(6):1251-1258.
Flory, M., M.K. Morphew, J.D. Joseph, A.R. Means, and T.N. Davis (2002). Pcp1p, a SPC110-related calmodulin target at the centrosome of the fission yeast, Schizosaccharomyces pombe. Cell Growth and Differentiation 13(2): 47-58.
Ladinsky, M.S., C.C. Wu, S. McIntosh, J.R. McIntosh and K.E. Howell (2002). Structure of the Golgi and distribution of reporter molecules at 20°C reveals the complexity of the exit compartments. Molecular Biology of the Cell 13: 2810-2825.
Marsh, B.J. and K.E. Howell (2002). The mammalian Golgi-complex debates. Nature Reviews Molecular Cell Biology 3:789-795.
McIntosh, J.R., M.S. Ladinsky, E.T. O'Toole, M.K. Morphew, J. Shimmin and D. Mastronarde (2002). Electron tomography of fast-frozen, freeze-substituted cells reveals 3-D features of membrane traffic and mitosis. ICEM 15:2003-2004.
O'Toole, E.T., M. Winey, J.R. McIntosh and D.N. Mastronarde (2002). Electron tomography of yeast cells. Methods in Enzymology. 351: 81-95.
Putkey, F.R., T. Cramer, M.K. Morphew, A.D. Silk, R.S. Johnson, J.R. McIntosh, and D.W. Cleveland (2002). Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Developmental Cell 3(3):351-365.
2001
Giddings, T.H., E.T. O'Toole, M.K. Morphew, D.N. Mastronarde, J.R. McIntosh and M. Winey (2001). Using rapid freezing and freeze-substitution for the preparation of yeast cells for electron microscopy and three-dimensional analysis. Methods in Cell Biology 67: 27-42.
Kniola, B., E.T. O'Toole, J.R. McIntosh, B. Mellone, R. Allshire, S. Mengarelli, K. Hultenby and K. Ekwall (2001). The domain structure of centromeres is conserved from fission yeast to humans. Molecular Biology of the Cell. 12: 2767-2775.
Marsh, B.J., D.N. Mastronarde, J.R. McIntosh and K.E. Howell (2001). Structural evidence for multiple transport mechanisms through the Golgi in the pancreatic beta-cell line, HIT-T15. Biochemical Society, Membrane Group/Neuorscience Group Joint Colloquium. 461-467.
Marsh, B.J., D.N. Mastronarde, K.F. Buttle, K.E. Howell and J.R. McIntosh (2001). Organellar relationships in the Golgi region of the pancreatic beta cell, line, HIT-T15, visualized by high-resolution electron tomography. Proceedings of the National Academy of Sciences 98: 2399-2406.
Otegui, M.S., D.N. Mastronarde, B.-H. Kang, S.Y. Bednarek and L.A. Staehelin (2001). Three-dimensional analysis of syncytial-type cell plates during endosperm cellularization visualized by high resolution electron tomography. Plant Cell 13: 2033-2051.
Rupp, G., E.T. O'Toole and M.E. Porter (2001). The Chlamydomonas PF6 locus encodes a large alanine/proline-rich polypeptide that is required for assembly of a central pair projection and regulates flagellar motility. Molecular Biology of the Cell 12: 739-751.
Winey, M., and E.T. O'Toole (2001). The spindle cycle in budding yeast. Nature Cell Biology 3: E23-27. abstract
2000
Morphew, M.K., D.N. Mastronarde, E.T. O'Toole, M.S. Ladinsky, B.J. Marsh, J. Kahana and J.R. McIntosh (2000). Three dimensional immunolocalization of green fluorescent protein chimeras using rapid freezing and freeze-substitution. Microscopy and Microanalysis, 298-299.
Perrone, C.A., S.H. Myster, R. Bower, E.T. O'Toole, and M.E. Porter (2000). Insights into the structural organization of the I1 inner dynein arm from a domain analysis of the 1b dynein heavy chain. Molecular Biology of the Cell 11: 2297-2313.
Wu, C.C., R.S. Taylor, D.R. Lane, M.S. Ladinsky, J.A. Weisz and K.E. Howell (2000). GMx33: A novel family of trans-Golgi proteins identified by proteomics. Traffic 1: 963-975.
1999
Balasundaram, D., M. Benedik, M.K. Morphew, V. Dang and H. Levine (1999). Nup124p is a nuclear pore factor of Schizosaccharomyces pombe that is important for the nuclear import and activity of the retrotransposon Tf1. Molecular Biology of the Cell 19: 5768-5784.
Hagan, I.M., A.J. Bridge, M.Morphew and R. Bartlett (1999). Cell cycle control and the mitotic spindle. British Journal of Cancer.
Ladinsky, M.S., D.N. Mastronarde, J.R. McIntosh, K.E. Howell and L.A. Staehelin (1999). Golgi structure in 3 dimensions: Functional insights from the NRK cell. Journal of Cell Biology, 144: 1135-1149.
McIntosh, J.R. and E.T. O'Toole (1999). Life cycles of yeast spindle pole bodies: getting microtubules into a closed nucleus. Biology of the Cell 91: 305-312.
Mitchell, D.R., and W.S. Sale (1999). Characterization of a Chlamydomonas insertional mutant that disrupts central pair microtubule-associated structures. Journal of Cell Biology 144: 293-304.
Morrell, J.L., M. Morphew, and K.L. Gould (1999). A Mutant of Arp2p Causes Partial Disassembly of the Arp2/3 Complex and loss of Cortical Actin Function in Fission Yeast. Molecular Biology of the Cell 10: 4201-4215.
Munoz-Centeno, M., S. McBratney, A. Monterrosa, B. Byers, C. Mann and M. Winey (1999). Saccharomyces cerevisiae MPS2 encodes a membrane protein localized at the spindle pole body and the nuclear envelope. Molecular Biology of the Cell 10: 2393-2406.
O'Toole, E.T., M. Winey and J.R. McIntosh (1999). High voltage electron tomography of spindle pole bodies and early mitotic spindles in the yeast, Saccharomyces cerevisiae. Molecular Biology of the Cell 10: 2017-2031.
Sparks, C.A., M.K. Morphew and D. McCollum (1999). Sid2p, a spindle pole body kinase that regulates the onset of cytokinesis. Journal of Cell Biology 146: 777-789.
Tirnauer, J.S., E.T. O'Toole, L. Berrueta, B.E. Bierer and D. Pellman (1999). Yeast Bim1p promotes the G1-specific dynamics of microtubules. Journal of Cell Biology 145: 993-1007.
Zeng, X., J.A. Kahana, P.A. Silver, M.K. Morphew, J.R. McIntosh, T.T. Fitch, J. Carbon and W.S. Saunders (1999). SLK19p is a centromere protein that functions to stabilize mitotic spindles. Journal of Cell Biology 26: 415-426.
1998
Bridge, A.J., M.K. Morphew , R. Bartlett and I. Hagan (1998). The fission yeast SPB component cut12 links bipolar spindle formation to mitotic control. Genes and Development 12(7): 927-42.
Perrone, C.A., P. Yang, W.S. Sale, and M.E. Porter (1998) The Chlamydomanas IDA7 locus encodes a 140 kDa dynein intermediate chain required to assemble the I1 inner arm complex. Molecular Biology of the Cell 9: 3351-3365.
West, R.R., E.V. Vaisberg, R. Ding, P. Nurse, and J.R. McIntosh (1998). Cut11: A Gene Required for Cell Cycle-dependent Spindle Pole Body Anchoring in the Nuclear Envelope and Bipolar Spindle Formation in Schizosaccharomyces pombe. Molecular Biology of the Cell 9: 2839-2855.
Wilkinson, C.R., Wallace, M., Morphew, M., Perry, P., Allshire, R., Javerrzatm, J.P., McIntosh, J.R., and Gordon, C. (1998). Localization of the 26s proteasome during mitosis and meiosis in fission yeast. EMBO Journal 17(22): 6465-76.
1997
Mastronarde, D.N. (1997). Dual-axis tomography: An approach with alignment methods that preserve resolution. Journal of Structural Biology 120: 343-352.
McIntosh, J.R., D.N Mastronarde, J.R. Kremer, E.T. O'Toole, M.S. Ladinsky, M.K. Morphew and K.L McDonald (1997). Three-dimensional reconstruction of cellular fine structure by electron microscopy of serial sections and serial tilts. In: Recent Advances in Microscopy of Cells, Tissues, and Organs (P.M.Motta, ed.) Antonio DelFino Editore, Rome. pp. 67-76.
Myster, S.H., J.A. Knott, E.T. O'Toole and M.E. Porter (1997). The Chlamydomonas Dhc1 gene encodes a dynein heavy chain subunit required for the assembly of the I1 inner arm complex. Molecular Biology of the Cell 8: 607-620.
O'Toole, E.T., D.N. Mastronarde, T.H. Giddings Jr., M. Winey, D.J. Burke and J.R. McIntosh (1997). Three-dimensional analysis and ultrastructural design of mitotic spindles from the cdc20 mutant of Saccharomyces cerevisiae. Molecular Biology of the Cell 8: 1-11.
Winey, M., D. Yarar, T.H. Giddings, Jr. and D.N. Mastronarde (1997). Nuclear pore complex number and distribution throughout the Saccharomyces cerevisiae cell cycle by three-dimensional reconstruction from electron micrographs of nuclear envelopes. Molecular Biology of the Cell 8: 2119-2132.
1996
Kremer J.R., D.N. Mastronarde and J.R. McIntosh (1996). Computer Visualization of Three-Dimensional Image Data Using IMOD. Journal of Structural Biology. 116: 71-76.
McCollum, D., A. Feoktistova, M.K. Morphew, M. Balasubramanian, and K. Gould (1996). The Schizosaccharomyces pombe actin-related protein, Arp3, is a component of the cortical actin cytoskeleton and interacts with profilin. EMBO Journal 15(23): 6438-46.
Rupp, G., E.T. O'Toole, L.C. Gardner, B.F. Mitchell and M.E. Porter (1996). The sup-pf-2 mutations of Chlamydomonas alter the activity of the outer dynein arms by modification of the gamma-dynein heavy chain. Journal of Cell Biology 135: 1853-1865.
Schlegel, A., T.H. Giddings, Jr., M.S. Ladinsky and K. Kirkegaard (1996). Cellular origin and ultrastructure of membranes induced during poliovirus infection. Journal of Virology 70:6576-6588.
1995
Demeter, J., M. Morphew and S. Sazar (1995). A mutation in the RCC1-related protein pim1 results in nuclear envelope fragmentation in fission yeast. Proceedings of the National Academy of Sciences 92(5): 1436-1440.
O'Toole, E.T., D.N. Mastronarde, J.R. McIntosh and M.E. Porter (1995). Computer-assisted analysis of flagellar structure. In: Methods in Cell Biology, Vol. 47. Cilia and Flagella (W. Dentler and G.Witman, eds.) Academic Press, San Diego. Pp. 183-191.
Wang, J., M.S. Ladinsky and K.E. Howell (1995). Molecules and vesicle coats involved in the budding of exocytotic vesicles from the trans-Golgi network. Cold Spring Harb. Symp. Quant. Biol. 60: 139-146.
Winey, M., C.L. Mamay, E.T. O'Toole, D.N. Mastronarde, T.H. Giddings, K.L. McDonald and J.R. McIntosh (1995). Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle. Journal of Cell Biology 129: 1601-1615.
1994
King, S.J., W.B. Inwood, E.T. O'Toole, J. Power and S.K. Dutcher (1994). The bop2-1 mutation reveals radial asymmetry in the inner dynein arm region of Chlamydomonas reinhardtii. Journal of Cell Biology 126: 1255-1266.
Ladinsky, M.S., J.R. Kremer, P.S. Furcinitti, J.R. McIntosh, and K.E. Howell (1994). HVEM tomography of the trans-Golgi network: Structural insights and identification of a lace-like vesicle coat. Journal of Cell Biology 127:29-38.
1993
Mastronarde, D.N., K.L. McDonald, R. Ding and J.R. McIntosh (1993). Interpolar spindle microtubules in PTK cells. Journal of Cell Biology 123: 1475-1489.
O'Toole, E.T., G. Wray, J.R. Kremer and J.R. McIntosh (1993). High voltage cryomicroscopy of human blood platelets. Journal of Structural Biology 110: 55-66.
1992
McDonald, K.L., E.T. O'Toole, D.N. Mastronarde and J.R. McIntosh (1992). Kinetochore microtubules in PTK cells. Journal of Cell Biology 118: 369-383.
Mastronarde, D.N., E.T. O'Toole, K.L. McDonald, J.R. McIntosh, and M.E. Porter (1992). Arrangement of inner dynein arms in wild-type and mutant flagella of Chlamydomonas. Journal of Cell Biology 118: 1145-1162.
Wilson, C.J., D.N. Mastronarde, B. McEwen and J. Frank (1992). Measurement of neuronal surface area using high-voltage electron microscope tomography. Neuroimage 1: 11-22.
1991
McDonald, K.L., D.N. Mastronarde, E.T. O'Toole and J.R McIntosh (1991). Computer-based tools for morphometric analysis of mitotic spindles and other microtubule systems. EMSA Bulletin 21: 1-6.
1989
McIntosh, J.R. and K.L. McDonald (1989). The Mitotic Spindle. Scientific American 261(4): 48-56.